Methylmalonic Acid - Serum

MMA

MMA may be ordered to help diagnose an early or mild B12 deficiency.  This test is done by blood testing.

Methylmalonic acid is a compound that reacts with vitamin B-12 to produce coenzyme A (CoA). Coenzyme A is essential to normal cellular function. When vitamin B-12 deficiencies occur, methylmalonic acid levels increase. Measurement of methylmalonic acid through the methylmalonic acid test can provide your doctor with information about an existing vitamin deficiency, especially if the B-12 deficiency is mild or just beginning.